In the closer example, we have some exquisite custom brackets that are so difficult to dismantle that even Sheldon Brown admits that a prospective thief who somehow got the whole bike back to his secret evil lair of thievery would still have a hell of a time removing the wheel.
On the other hand, the farther bike goes for the color-coordinated DIY zip-tie method which, while perhaps not quite as secure, nonetheless would certainly still be a hassle to remove. And it looks quite stylish too! However, god forbid you actually have to remove the wheel from your frame–seems like it would be just as much of an ordeal for you as it would for the thieves.
Of course, we all know that all bicycles are on temporary loan from the universe, so it’s only a matter of time before something happens to yours. The best thing you can do is make it as difficult as possible on the jerks!